Trulicity (Dulaglutide) for Weight Loss: Safe and Effective Solutions

Trulicity® (dulaglutide) is a prescription medication primarily used to improve blood sugar control in
adults with type 2 diabetes. It is also indicated to reduce the risk of major cardiovascular events such
as heart attack, stroke, or death in adults with type 2 diabetes who have established cardiovascular
disease. Trulicity is a once-weekly subcutaneous injection and is part of a class of drugs known as
GLP-1 receptor agonists.

Table of Contents:

  1. What is Trulicity?
  2. How does Trulicity work?
  3. Side Effects and Warnings
  4. Usage Instructions
  5. Special Considerations
  6. Drug Interactions and Contraindications
  7. Storage
  8. >Disclaimer

What is Trulicity?

  • Active Ingredient: Dulaglutide.
  • Drug Class: GLP-1 receptor agonist.
  • Indications: Type 2 diabetes in adults; cardiovascular risk reduction in adults with type 2
    diabetes and established cardiovascular disease.
  • Administration: Subcutaneous injection once a week.
  • Available Strengths:0.75 mg, 1.5 mg, 3 mg, and 4.5 mg in single-dose pens.

How Does Trulicity Work?

  • Trulicity mimics the action of the incretin GLP-1, which is involved in the regulation of blood
    sugar. It increases insulin secretion in response to meals, decreases the amount of glucose produced
    by the liver, and slows gastric emptying to help control appetite and food intake

Side Effects and Warnings

  • Common Side Effects:Include nausea, diarrhea, vomiting, abdominal pain, decreased appetite,
    indigestion, and fatigue.
  • Serious Side Effects: Can include pancreatic inflammation (pancreatitis), serious allergic
    reactions, kidney failure, and severe gastrointestinal problems. Immediate medical attention is
    required for serious side effects.
  • Warnings: Not recommended for individuals with a personal or family history of medullary
    thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Usage Instructions

  • Dosage: Begins with a lower dose and may be increased based on the individual’s needs and
    tolerability. The injection is administered once a week, at any time of the day, with or without
    meals, in the thigh, abdomen, or upper arm.
  • Rotate the injection site with each dose to reduce the risk of lipodystrophy.

Special Considerations

  • Pregnancy and Breastfeeding:The effects on pregnancy and breastfeeding are not well
    established. It should be used during pregnancy only if the potential benefit justifies the
    potential risk to the fetus.

Drug Interactions and Contraindications

  • It is important to inform your healthcare provider about all the medications you take, including
    prescription and over-the-counter medicines, vitamins, and herbal supplements. Trulicity may
    interact with other diabetes medications, increasing the risk of hypoglycemia.


  • Store in the refrigerator at 36°F to 46°F (2°C to 8°C). Do not freeze. It can be kept at room
    temperature, up to 86°F (30°C), for up to 14 days.


Trulicity® is a prescription medication and should only be used under the guidance of a healthcare
professional. The information provided here is for educational purposes only and is not a substitute for
professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for any
questions regarding your health or medications. The brand name ‘Trulicity®’ is used for informational
purposes and does not imply endorsement of any specific medication, service, or treatment. The
information is compiled from various sources and may change. It does not cover all possible uses,
actions, precautions, side effects, or interactions of the drug. For more detailed information, refer to
the official prescribing information and consult with healthcare providers.