Rybelsus (Semaglutide)

Rybelsus (semaglutide) tablets are a prescription medicine used primarily for adults with type 2
diabetes mellitus to control blood sugar levels. While not an FDA-approved weight loss medicine,
Rybelsus has been shown to help with weight loss in studies. It is taken once a day in tablet form, in
conjunction with diet and exercise.

Table of Contents:

  1. What is Rybelsus?
  2. How does Rybelsus work?
  3. Side Effects and Warnings
  4. Usage Instructions
  5. Special Considerations
  6. Drug Interactions and Contraindications
  7. Storage
  8. Disclaimer

What is Rybelsus?

  • Active Ingredient: Semaglutide.
  • Drug Class: GLP-1 receptor agonists.
  • Indications: Type 2 diabetes in adults.
  • Administration: Oral tablet, usually once per day.
  • Available Strengths: 7 mg or 14 mg tablets.

How Does Rybelsus Work?

  • Rybelsus works by increasing insulin release and decreasing glucagon secretion. This helps lower
    blood sugar levels and may also slow gastric emptying after eating, contributing to a feeling of

Side Effects and Warnings

  • Common Side Effects: May include nausea, upset stomach, heartburn, burping, gas, bloating,
    vomiting, stomach pain, loss of appetite, diarrhea, constipation, runny nose, sore throat, headache,
    dizziness, and tiredness.
  • Serious Side Effects: Include pancreatitis, vision changes, thyroid tumors, gallbladder
    problems, low blood sugar, kidney problems, and serious allergic reactions. Immediate medical
    attention is required for serious side effects.
  • Warnings: Not suitable for those with multiple endocrine neoplasia type 2, a personal or
    family history of medullary thyroid cancer, insulin-dependent diabetes, or diabetic ketoacidosis. It
    is not known whether Rybelsus is safe and effective in children under 18 years of age or for use in
    people who have had pancreatitis.

Usage Instructions

  • Rybelsus should be taken exactly as prescribed by the doctor. It should be taken by mouth on an
    empty stomach when you first wake up with a small amount of water and should be swallowed whole.

Special Considerations

  • Pregnancy and Breastfeeding: Not recommended for use in pregnancy and breastfeeding. It is
    not known if Rybelsus will harm an unborn baby, and breastfeeding is not recommended during
    treatment with Rybelsus.

Drug Interactions and Contraindications

  • Inform your healthcare provider about all the medicines you take, as Rybelsus may affect the way
    some medicines work and vice versa.


  • Store Rybelsus in the original package at room temperature, away from moisture and heat.


Rybelsus is a prescription medication and should only be used under the guidance of a healthcare
professional. The information provided here is for educational purposes only and is not a substitute for
professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for any
questions regarding your health or medications. The brand name ‘Rybelsus’ is used for informational
purposes and does not imply endorsement of any specific medication, service, or treatment. The
information is compiled from various sources and may change. It does not cover all possible uses,
actions, precautions, side effects, or interactions of the drug. For more detailed information, refer to
the official prescribing information and consult with healthcare providers.